Interactions between proteins are essential to any cellular process and constitute the basis for molecular networks that determine the functional state of a cell. Defining the interactome of OGT, the sole enzyme adding the O-GlcNAc onto its target proteins, can facilitate studies in OGT biology, protein O-GlcNAcylation, functional elucidation of proteins/pathways/processes, drug development, and others.
OGT Protein Interaction Network (OGT-PIN) is a curated and comprehensive database of experimentally identified interaction proteins of OGT and its orthologues in multiple species studied in the past several decades.
The current version: OGT-PIN_2.0
If you find this resource helpful, please cite our paper:
Ma J., et al., OGT Protein Interaction Network (OGT-PIN): A Curated Database of Experimentally Identified Interaction Proteins of OGT. Int. J. Mol. Sci. 2021, 22(17), 9620. DOI: 10.3390/ijms22179620.