Community resources for O-GlcNAc biology
oglcnac.org
Search curated O-GlcNAc sites and OGT interactions, predict sites from FASTA, and classify glycoforms in one portal.
Resource suite
Four tools for complementary research questions
O-GlcNAcAtlas
Search and browse experimentally identified O-GlcNAc proteins and modification sites.
OGT-PIN
Explore curated interaction proteins of OGT and its orthologues across experimental reports.
O-GlcNAcPRED-DL
Predict protein O-GlcNAcylation sites from FASTA input using ensemble deep learning.
HexNAcQuest
Distinguish O-GlcNAc and O-GalNAc signals in glycoproteomics analysis.
Why it matters
O-GlcNAc biology, from evidence to hypothesis
O-linked beta-N-acetylglucosamine is a dynamic post-translational modification on serine, threonine, and tyrosine residues. It is regulated by OGT and OGA and has been implicated in transcription, translation, cell-cycle control, metabolism, and signaling.
oglcnac.org brings together curated evidence and predictive tools so researchers can move from a protein or sequence to sites, interactors, candidate predictions, and testable hypotheses.
Integrated workflow
Choose a tool by input
- Protein or site: search O-GlcNAcAtlas.
- OGT interactor: search OGT-PIN.
- FASTA sequence: run O-GlcNAcPRED-DL.
- Oxonium-ion intensities: run HexNAcQuest.
- Downstream analysis: download curated datasets and filtered results.
Start here