Details for Accession #: Q9ULT8

Protein Sequence

>sp|Q9ULT8|HECD1_HUMAN E3 ubiquitin-protein ligase HECTD1 OS=Homo sapiens OX=9606 GN=HECTD1 PE=1 SV=4
MADVDPDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRCFETCPPRTFLPALCKI
FLDESAPDNVLEVTARAITYYLDVSAECTRRIVGVDGAIKALCNRLVVVELNNRTSRDLA
EQCVKVLELICTRESGAVFEAGGLNCVLTFIRDSGHLVHKDTLHSAMAVVSRLCGKMEPQ
DSSLEICVESLSSLLKHEDHQVSDGALRCFASLADRFTRRGVDPAPLAKHGLTEELLSRM
AAAGGTVSGPSSACKPGRSTTGAPSTTADSKLSNQVSTIVSLLSTLCRGSPVVTHDLLRS
ELPDSIESALQGDERCVLDTMRLVDLLLVLLFEGRKALPKSSAGSTGRIPGLRRLDSSGE
RSHRQLIDCIRSKDTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGA
DVNRGQRSSSLHYAACFGRPQVAKTLLRHGANPDLRDEDGKTPLDKARERGHSEVVAILQ
SPGDWMCPVNKGDDKKKKDTNKDEEECNEPKGDPEMAPIYLKRLLPVFAQTFQQTMLPSI
RKASLALIRKMIHFCSEALLKEVCDSDVGHNLPTILVEITATVLDQEDDDDGHLLALQII
RDLVDKGGDIFLDQLARLGVISKVSTLAGPSSDDENEEESKPEKEDEPQEDAKELQQGKP
YHWRDWSIIRGRDCLYIWSDAAALELSNGSNGWFRFILDGKLATMYSSGSPEGGSDSSES
RSEFLEKLQRARGQVKPSTSSQPILSAPGPTKLTVGNWSLTCLKEGEIAIHNSDGQQATI
LKEDLPGFVFESNRGTKHSFTAETSLGSEFVTGWTGKRGRKLKSKLEKTKQKVRTMARDL
YDDHFKAVESMPRGVVVTLRNIATQLESSWELHTNRQCIESENTWRDLMKTALENLIVLL
KDENTISPYEMCSSGLVQALLTVLNNSMDLDMKQDCSQLVERINVFKTAFSENEDDESRP
AVALIRKLIAVLESIERLPLHLYDTPGSTYNLQILTRRLRFRLERAPGETALIDRTGRML
KMEPLATVESLEQYLLKMVAKQWYDFDRSSFVFVRKLREGQNFIFRHQHDFDENGIIYWI
GTNAKTAYEWVNPAAYGLVVVTSSEGRNLPYGRLEDILSRDNSALNCHSNDDKNAWFAID
LGLWVIPSAYTLRHARGYGRSALRNWVFQVSKDGQNWTSLYTHVDDCSLNEPGSTATWPL
DPPKDEKQGWRHVRIKQMGKNASGQTHYLSLSGFELYGTVNGVCEDQLGKAAKEAEANLR
RQRRLVRSQVLKYMVPGARVIRGLDWKWRDQDGSPQGEGTVTGELHNGWIDVTWDAGGSN
SYRMGAEGKFDLKLAPGYDPDTVASPKPVSSTVSGTTQSWSSLVKNNCPDKTSAAAGSSS
RKGSSSSVCSVASSSDISLGSTKTERRSEIVMEHSIVSGADVHEPIVVLSSAENVPQTEV
GSSSSASTSTLTAETGSENAERKLGPDSSVRTPGESSAISMGIVSVSSPDVSSVSELTNK
EAASQRPLSSSASNRLSVSSLLAAGAPMSSSASVPNLSSRETSSLESFVRRVANIARTNA
TNNMNLSRSSSDNNTNTLGRNVMSTATSPLMGAQSFPNLTTPGTTSTVTMSTSSVTSSSN
VATATTVLSVGQSLSNTLTTSLTSTSSESDTGQEAEYSLYDFLDSCRASTLLAELDDDED
LPEPDEEDDENEDDNQEDQEYEEVMILRRPSLQRRAGSRSDVTHHAVTSQLPQVPAGAGS
RPIGEQEEEEYETKGGRRRTWDDDYVLKRQFSALVPAFDPRPGRTNVQQTTDLEIPPPGT
PHSELLEEVECTPSPRLALTLKVTGLGTTREVELPLTNFRSTIFYYVQKLLQLSCNGNVK
SDKLRRIWEPTYTIMYREMKDSDKEKENGKMGCWSIEHVEQYLGTDELPKNDLITYLQKN
ADAAFLRHWKLTGTNKSIRKNRNCSQLIAAYKDFCEHGTKSGLNQGAISTLQSSDILNLT
KEQPQAKAGNGQNSCGVEDVLQLLRILYIVASDPYSRISQEDGDEQPQFTFPPDEFTSKK
ITTKILQQIEEPLALASGALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQN
RREATVERTRTTSSVRRDDPGEFRVGRLKHERVKVPRGESLMEWAENVMQIHADRKSVLE
VEFLGEEGTGLGPTLEFYALVAAEFQRTDLGAWLCDDNFPDDESRHVDLGGGLKPPGYYV
QRSCGLFTAPFPQDSDELERITKLFHFLGIFLAKCIQDNRLVDLPISKPFFKLMCMGDIK
SNMSKLIYESRGDRDLHCTESQSEASTEEGHDSLSVGSFEEDSKSEFILDPPKPKPPAWF
NGILTWEDFELVNPHRARFLKEIKDLAIKRRQILSNKGLSEDEKNTKLQELVLKNPSGSG
PPLSIEDLGLNFQFCPSSRIYGFTAVDLKPSGEDEMITMDNAEEYVDLMFDFCMHTGIQK
QMEAFRDGFNKVFPMEKLSSFSHEEVQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGF
LRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKVDATDASYPSVNTCV
HYLKLPEYSSEEIMRERLLAATMEKGFHLN

Peptide Information

ID Peptide Seq Site Residue Position in Peptide Position in Protein
5253 LAPGYDPDTVASPKPVSSTVSGTTQSWSSLVK T 1342.0
5254 LAPGYDPDTVASPKPVSSTVSGTTQSWSSLVK S 1351.0
5255 LTGTNKSIR T 1932.0
5256 TTSSVR S 2114.0
5827 LSVSSLLAAGAPMSSSASVPNLSSR S 16 1531.0
5941 LSVSSLLAAGAPMSSSASVPNLSSR S 2 1517.0
10003542 PVSSTVSGTTQSWSSLVK S 3 1350
10004884 TALENLIVLLK T 1 891
10006496 SELTNKEAASQRPLSSSASNRLSVSSLLAAG S 1510
10006497 NIARTNATNNMNLSRSSSDNNTNTLGRNVMS S 1569
10006498 IARTNATNNMNLSRSSSDNNTNTLGRNVMST S 1570
10009122 LAPGYDPDTVASPKPVSSTVSGTTQSWSSLVK S 12 1345
10009504 SSSDNNTNTLGR S 1 1569
10009505 SSSDNNTNTLGR S 2 1570
10009506 SSSDNNTNTLGR S 3 1571
10011370 EAASQRPLSSSASNR S 10 1510
10011371 LSVSSLLAAGAPMSSSASVPNLSSR S 15 1530
10011629 TSAAAGSSSRK S 2 1373
10011630 TSAAAGSSSRK T 1 1372
10017022 PVSSTVSGTTQSWSSLVK S 3 1350
10017023 SSSDNNTNTLGR S 1 1569
10017512 LAPGYDPDTVASPKPVSSTVSGTTQSWSSLVK S 12 1345
10017513 LAPGYDPDTVASPKPVSSTVSGTTQSWSSLVK S 12 1345
10017523 SSSDNNTNTLGR S 1 1569
10017524 SSSDNNTNTLGR S 1 1569
10017590 SSSDNNTNTLGR S 2 1570
10017591 SSSDNNTNTLGR S 3 1571
10017824 SSSDNNTNTLGR S 2 1570
10017825 SSSDNNTNTLGR S 3 1571
10019147 1350
10019148 1569
10020876 1569
10021903 1569
10021928 1350
10024220 1350
10025538 TSAAAGSSSRK S 1373
10025539 TSAAAGSSSRK T 1372
10026493 KGSSSSVCSVASSSDISLGSTKTER S 12 1393
10026494 LAPGYDPDTVASPKPVSSTVSGTTQSWSSLVK T 19 1352
10026495 LAPGYDPDTVASPKPVSSTVSGTTQSWSSLVK T 23 1356
10026496 LAPGYDPDTVASPKPVSSTVSGTTQSWSSLVK T 24 1357
10026804 PVSSTVSGTTQSWSSLVK S 3 1350
10026854 SSSDNNTNTLGR S 1 1569
10028004 LAPGYDPDTVASPKPVSSTVSGTTQSWSSLVK S 17 1350
10029797 PVSSTVSGTTQSWSSLVK S 3 1350
10030867 PVSSTVSGTTQSWSSLVK S 3 1350
10031700 S 1350
10034153 EAASQRPLSSSASNR S 1510
10034154 LAPGYDPDTVASPKPVSSTVSGTTQSWSSLVK S 1350
10034155 SSSDNNTNTLGR S 1569
10035395 SSSDNNTNTLGR S 1 1569

O-GlcNAcylation Information

ID Method Analytical Throughput Ambiguity Species Sample Type Data Source PMID Comments
5253 MS HTP None human T cells 29351928 None
5254 MS HTP None human T cells 29351928 None
5255 MS HTP None human T cells 29351928 None
5256 MS HTP None human T cells 29351928 None
5827 MS HTP None human HeLa cells 31373491 None
5941 MS HTP None human HeLa cells 31373491 None
10003542 MS HTP None human HeLa cells 28604694 None
10004884 MS HTP None human T cells 29351928 None
10006496 MS HTP None human HeLa cells 30059200 None
10006497 MS HTP None human HeLa cells 30059200 None
10006498 MS HTP None human HeLa cells 30059200 None
10009122 MS HTP None human HEK 293T cells 30620550 None
10009504 MS HTP None human HEK 293T cells 30620550 None
10009505 MS HTP None human HEK 293T cells 30620550 None
10009506 MS HTP None human HEK 293T cells 30620550 None
10011370 MS HTP None human HeLa cells 31492838 None
10011371 MS HTP None human HeLa cells 31492838 None
10011629 MS HTP None human liver 31637018 None
10011630 MS HTP None human liver 31637018 None
10017022 MS HTP None human HeLa cells 30059200 None
10017023 MS HTP None human HeLa cells 30059200 None
10017512 MS HTP None human HepG2 cells 30620550 None
10017513 MS HTP None human HEK 293T cells 30620550 None
10017523 MS HTP None human HepG2 cells 30620550 None
10017524 MS HTP None human HEK 293T cells 30620550 None
10017590 MS HTP None human HepG2 cells 30620550 None
10017591 MS HTP None human HepG2 cells 30620550 None
10017824 MS HTP None human HEK 293T cells 30620550 None
10017825 MS HTP None human HEK 293T cells 30620550 None
10019147 MS HTP None human HeLa cells 34161081 None
10019148 MS HTP None human HeLa cells 34161081 None
10020876 MS HTP None human HeLa cells 34161081 None
10021903 MS HTP None human HeLa cells 34161081 None
10021928 MS HTP None human HeLa cells 34161081 None
10024220 MS HTP None human colorectal cancer (CRC) cell lines 35254053 None
10025538 MS HTP None human liver 31637018 None
10025539 MS HTP None human liver 31637018 None
10026493 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10026494 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10026495 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10026496 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10026804 MS HTP None human HeLa cells 35254053 None
10026854 MS HTP None human HeLa cells 35254053 None
10028004 MS HTP None human HeLa cells 35254053 None
10029797 MS HTP None human SW480 cells 35254053 None
10030867 MS HTP None human SW620 cells 35254053 None
10031700 MS HTP None human SW480 cells, SW620 cells 35254053 None
10034153 MS HTP None human MCF-7 cells 35513511 None
10034154 MS HTP None human MCF-7 cells 35513511 None
10034155 MS HTP None human MCF-7 cells 35513511 None
10035395 MS HTP None human Jurkat cells 35705054 None
ID Peptide Seq Site Residue Position in Peptide Position in Protein Method Analytical Throughput Ambiguity Species Sample Type Data Source PMID Comments
5253 LAPGYDPDTVASPKPVSSTVSGTTQSWSSLVK T 1342.0 MS HTP None human T cells 29351928 None
5254 LAPGYDPDTVASPKPVSSTVSGTTQSWSSLVK S 1351.0 MS HTP None human T cells 29351928 None
5255 LTGTNKSIR T 1932.0 MS HTP None human T cells 29351928 None
5256 TTSSVR S 2114.0 MS HTP None human T cells 29351928 None
5827 LSVSSLLAAGAPMSSSASVPNLSSR S 16 1531.0 MS HTP None human HeLa cells 31373491 None
5941 LSVSSLLAAGAPMSSSASVPNLSSR S 2 1517.0 MS HTP None human HeLa cells 31373491 None
10003542 PVSSTVSGTTQSWSSLVK S 3 1350 MS HTP None human HeLa cells 28604694 None
10004884 TALENLIVLLK T 1 891 MS HTP None human T cells 29351928 None
10006496 SELTNKEAASQRPLSSSASNRLSVSSLLAAG S 1510 MS HTP None human HeLa cells 30059200 None
10006497 NIARTNATNNMNLSRSSSDNNTNTLGRNVMS S 1569 MS HTP None human HeLa cells 30059200 None
10006498 IARTNATNNMNLSRSSSDNNTNTLGRNVMST S 1570 MS HTP None human HeLa cells 30059200 None
10009122 LAPGYDPDTVASPKPVSSTVSGTTQSWSSLVK S 12 1345 MS HTP None human HEK 293T cells 30620550 None
10009504 SSSDNNTNTLGR S 1 1569 MS HTP None human HEK 293T cells 30620550 None
10009505 SSSDNNTNTLGR S 2 1570 MS HTP None human HEK 293T cells 30620550 None
10009506 SSSDNNTNTLGR S 3 1571 MS HTP None human HEK 293T cells 30620550 None
10011370 EAASQRPLSSSASNR S 10 1510 MS HTP None human HeLa cells 31492838 None
10011371 LSVSSLLAAGAPMSSSASVPNLSSR S 15 1530 MS HTP None human HeLa cells 31492838 None
10011629 TSAAAGSSSRK S 2 1373 MS HTP None human liver 31637018 None
10011630 TSAAAGSSSRK T 1 1372 MS HTP None human liver 31637018 None
10017022 PVSSTVSGTTQSWSSLVK S 3 1350 MS HTP None human HeLa cells 30059200 None
10017023 SSSDNNTNTLGR S 1 1569 MS HTP None human HeLa cells 30059200 None
10017512 LAPGYDPDTVASPKPVSSTVSGTTQSWSSLVK S 12 1345 MS HTP None human HepG2 cells 30620550 None
10017513 LAPGYDPDTVASPKPVSSTVSGTTQSWSSLVK S 12 1345 MS HTP None human HEK 293T cells 30620550 None
10017523 SSSDNNTNTLGR S 1 1569 MS HTP None human HepG2 cells 30620550 None
10017524 SSSDNNTNTLGR S 1 1569 MS HTP None human HEK 293T cells 30620550 None
10017590 SSSDNNTNTLGR S 2 1570 MS HTP None human HepG2 cells 30620550 None
10017591 SSSDNNTNTLGR S 3 1571 MS HTP None human HepG2 cells 30620550 None
10017824 SSSDNNTNTLGR S 2 1570 MS HTP None human HEK 293T cells 30620550 None
10017825 SSSDNNTNTLGR S 3 1571 MS HTP None human HEK 293T cells 30620550 None
10019147 1350 MS HTP None human HeLa cells 34161081 None
10019148 1569 MS HTP None human HeLa cells 34161081 None
10020876 1569 MS HTP None human HeLa cells 34161081 None
10021903 1569 MS HTP None human HeLa cells 34161081 None
10021928 1350 MS HTP None human HeLa cells 34161081 None
10024220 1350 MS HTP None human colorectal cancer (CRC) cell lines 35254053 None
10025538 TSAAAGSSSRK S 1373 MS HTP None human liver 31637018 None
10025539 TSAAAGSSSRK T 1372 MS HTP None human liver 31637018 None
10026493 KGSSSSVCSVASSSDISLGSTKTER S 12 1393 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10026494 LAPGYDPDTVASPKPVSSTVSGTTQSWSSLVK T 19 1352 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10026495 LAPGYDPDTVASPKPVSSTVSGTTQSWSSLVK T 23 1356 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10026496 LAPGYDPDTVASPKPVSSTVSGTTQSWSSLVK T 24 1357 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10026804 PVSSTVSGTTQSWSSLVK S 3 1350 MS HTP None human HeLa cells 35254053 None
10026854 SSSDNNTNTLGR S 1 1569 MS HTP None human HeLa cells 35254053 None
10028004 LAPGYDPDTVASPKPVSSTVSGTTQSWSSLVK S 17 1350 MS HTP None human HeLa cells 35254053 None
10029797 PVSSTVSGTTQSWSSLVK S 3 1350 MS HTP None human SW480 cells 35254053 None
10030867 PVSSTVSGTTQSWSSLVK S 3 1350 MS HTP None human SW620 cells 35254053 None
10031700 S 1350 MS HTP None human SW480 cells, SW620 cells 35254053 None
10034153 EAASQRPLSSSASNR S 1510 MS HTP None human MCF-7 cells 35513511 None
10034154 LAPGYDPDTVASPKPVSSTVSGTTQSWSSLVK S 1350 MS HTP None human MCF-7 cells 35513511 None
10034155 SSSDNNTNTLGR S 1569 MS HTP None human MCF-7 cells 35513511 None
10035395 SSSDNNTNTLGR S 1 1569 MS HTP None human Jurkat cells 35705054 None