Details for Accession #: Q9HCK8

Protein Sequence

>sp|Q9HCK8|CHD8_HUMAN Chromodomain-helicase-DNA-binding protein 8 OS=Homo sapiens OX=9606 GN=CHD8 PE=1 SV=5
MADPIMDLFDDPNLFGLDSLTDDSFNQVTQDPIEEALGLPSSLDSLDQMNQDGGGGDVGN
SSASELVPPPEETAPTELSKESTAPAPESITLHDYTTQPASQEQPAQPVLQTSTPTSGLL
QVSKSQEILSQGNPFMGVSATAVSSSSAGGQPPQSAPKIVILKAPPSSSVTGAHVAQIQA
QGITSTAQPLVAGTANGGKVTFTKVLTGTPLRPGVSIVSGNTVLAAKVPGNQAAVQRIVQ
PSRPVKQLVLQPVKGSAPAGNPGATGPPLKPAVTLTSTPTQGESKRITLVLQQPQSGGPQ
GHRHVVLGSLPGKIVLQGNQLAALTQAKNAQGQPAKVVTIQLQVQQPQQKIQIVPQPPSS
QPQPQQPPSTQPVTLSSVQQAQIMGPGQSPGQRLSVPVKVVLQPQAGSSQGASSGLSVVK
VLSASEVAALSSPASSAPHSGGKTGMEENRRLEHQKKQEKANRIVAEAIARARARGEQNI
PRVLNEDELPSVRPEEEGEKKRRKKSAGERLKEEKPKKSKTSGASKTKGKSKLNTITPVV
GKKRKRNTSSDNSDVEVMPAQSPREDEESSIQKRRSNRQVKRKKYTEDLDIKITDDEEEE
EVDVTGPIKPEPILPEPVQEPDGETLPSMQFFVENPSEEDAAIVDKVLSMRIVKKELPSG
QYTEAEEFFVKYKNYSYLHCEWATISQLEKDKRIHQKLKRFKTKMAQMRHFFHEDEEPFN
PDYVEVDRILDESHSIDKDNGEPVIYYLVKWCSLPYEDSTWELKEDVDEGKIREFKRIQS
RHPELKRVNRPQASAWKKLELSHEYKNRNQLREYQLEGVNWLLFNWYNRQNCILADEMGL
GKTIQSIAFLQEVYNVGIHGPFLVIAPLSTITNWEREFNTWTEMNTIVYHGSLASRQMIQ
QYEMYCKDSRGRLIPGAYKFDALITTFEMILSDCPELREIEWRCVIIDEAHRLKNRNCKL
LDSLKHMDLEHKVLLTGTPLQNTVEELFSLLHFLEPSQFPSESEFLKDFGDLKTEEQVQK
LQAILKPMMLRRLKEDVEKNLAPKQETIIEVELTNIQKKYYRAILEKNFSFLSKGAGHTN
MPNLLNTMMELRKCCNHPYLINGAEEKILTEFREACHIIPHDFHLQAMVRSAGKLVLIDK
LLPKLKAGGHKVLIFSQMVRCLDILEDYLIQRRYLYERIDGRVRGNLRQAAIDRFSKPDS
DRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITR
NSYEREMFDKASLKLGLDKAVLQSMSGRDGNITGIQQFSKKEIEDLLRKGAYAAIMEEDD
EGSKFCEEDIDQILLRRTTTITIESEGKGSTFAKASFVASENRTDISLDDPNFWQKWAKK
ADLDMDLLNSKNNLVIDTPRVRKQTRHFSTLKDDDLVEFSDLESEDDERPRSRRHDRHHA
YGRTDCFRVEKHLLVYGWGRWRDILSHGRFKRRMTERDVETICRAILVYCLLHYRGDENI
KGFIWDLISPAENGKTKELQNHSGLSIPVPRGRKGKKVKSQSTFDIHKADWIRKYNPDTL
FQDESYKKHLKHQCNKVLLRVRMLYYLRQEVIGDQAEKVLGGAIASEIDIWFPVVDQLEV
PTTWWDSEADKSLLIGVFKHGYEKYNTMRADPALCFLEKAGRPDDKAIAAEHRVLDNFSD
IVEGVDFDKDCEDPEYKPLQGPPKDQDDEGDPLMMMDEEISVIDGDEAQVTQQPGHLFWP
PGSALTARLRRLVTAYQRSYKREQMKIEAAERGDRRRRRCEAAFKLKEIARREKQQRWTR
REQTDFYRVVSTFGVEYDPDTMQFHWDRFRTFARLDKKTDESLTKYFHGFVAMCRQVCRL
PPAAGDEPPDPNLFIEPITEERASRTLYRIELLRRLREQVLCHPLLEDRLALCQPPGPEL
PKWWEPVRHDGELLRGAARHGVSQTDCNIMQDPDFSFLAARMNYMQNHQAGAPAPSLSRC
STPLLHQQYTSRTASPLPLRPDAPVEKSPEETATQVPSLESLTLKLEHEVVARSRPTPQD
YEMRVSPSDTTPLVSRSVPPVKLEDEDDSDSELDLSKLSPSSSSSSSSSSSSSSTDESED
EKEEKLTDQSRSKLYDEESLLSLTMSQDGFPNEDGEQMTPELLLLQERQRASEWPKDRVL
INRIDLVCQAVLSGKWPSSRRSQEMVTGGILGPGNHLLDSPSLTPGEYGDSPVPTPRSSS
AASMAEEEASAVSTAAAQFTKLRRGMDEKEFTVQIKDEEGLKLTFQKHKLMANGVMGDGH
PLFHKKKGNRKKLVELEVECMEEPNHLDVDLETRIPVINKVDGTLLVGEDAPRRAELEMW
LQGHPEFAVDPRFLAYMEDRRKQKWQRCKKNNKAELNCLGMEPVQTANSRNGKKGHHTET
VFNRVLPGPIAPESSKKRARRMRPDLSKMMALMQGGSTGSLSLHNTFQHSSSGLQSVSSL
GHSSATSASLPFMPFVMGGAPSSPHVDSSTMLHHHHHHPHPHHHHHHHPGLRAPGYPSSP
VTTASGTTLRLPPLQPEEDDDEDEEDDDDLSQGYDSSERDFSLIDDPMMPANSDSSEDAD
D

Peptide Information

ID Peptide Seq Site Residue Position in Peptide Position in Protein
5003 ESTAPAPESITLHDYTTQPASQEQPAQPVLQTSTPTSGLLQVSK S 113.0
5004 ESTAPAPESITLHDYTTQPASQEQPAQPVLQTSTPTSGLLQVSK S 117.0
5917 APGYPSSPVTTASGTTLR T 15 2527.0
6107 APGYPSSPVTTASGTTLR T 10 2522.0
6209 AVLQSMSGR S 7 1286.0
10004594 ESTAPAPESITLHDYTTQPASQEQPAQPVLQTSTPTSGLLQVSK S 43 123
10019702 171
10021163 171
10021739 171
10023365 APPSSSVTGAHVAQIQAQGITSTAQPLVAGTANGGK S 7 169
10024537 2522
10025308 ESTAPAPESITLHDYTTQPASQEQPAQPVLQTSTPTSGLLQVSK T 34 114
10025309 ESTAPAPESITLHDYTTQPASQEQPAQPVLQTSTPTSGLLQVSK S 43 123
10027099 APGYPSSPVTTASGTTLR S 7 2519
10027102 APPSSSVTGAHVAQIQAQGITSTAQPLVAGTANGGK T 8 171
10027591 APGYPSSPVTTASGTTLR T 11 2523
10027767 APGYPSSPVTTASGTTLR T 10 2522
10027999 GSAPAGNPGATGPPLKPAVTLTSTPTQGESK S 2 256
10028930 APPSSSVTGAHVAQIQAQGITSTAQPLVAGTANGGK T 21 184
10031189 APGYPSSPVTTASGTTLR T 10 2522
10031379 GSAPAGNPGATGPPLKPAVTLTSTPTQGESK S 2 256
10031991 T 2522

O-GlcNAcylation Information

ID Method Analytical Throughput Ambiguity Species Sample Type Data Source PMID Comments
5003 MS HTP None human T cells 29351928 None
5004 MS HTP None human T cells 29351928 None
5917 MS HTP None human HeLa cells 31373491 None
6107 MS HTP None human HeLa cells 31373491 None
6209 MS HTP None human HeLa cells 31373491 None
10004594 MS HTP None human T cells 29351928 None
10019702 MS HTP None human HeLa cells 34161081 None
10021163 MS HTP None human HeLa cells 34161081 None
10021739 MS HTP None human HeLa cells 34161081 None
10023365 MS HTP None human HeLa cells 34846842 None
10024537 MS HTP None human colorectal cancer (CRC) cell lines 35254053 None
10025308 MS HTP None human THP1 cells 32938750 None
10025309 MS HTP None human THP1 cells 32938750 None
10027099 MS HTP None human HeLa cells 35254053 None
10027102 MS HTP None human HeLa cells 35254053 None
10027591 MS HTP None human HeLa cells 35254053 None
10027767 MS HTP None human HeLa cells 35254053 None
10027999 MS HTP None human HeLa cells 35254053 None
10028930 MS HTP None human HeLa cells 35254053 None
10031189 MS HTP None human SW620 cells 35254053 None
10031379 MS HTP None human SW620 cells 35254053 None
10031991 MS HTP None human SW480 cells, SW620 cells 35254053 None
ID Peptide Seq Site Residue Position in Peptide Position in Protein Method Analytical Throughput Ambiguity Species Sample Type Data Source PMID Comments
5003 ESTAPAPESITLHDYTTQPASQEQPAQPVLQTSTPTSGLLQVSK S 113.0 MS HTP None human T cells 29351928 None
5004 ESTAPAPESITLHDYTTQPASQEQPAQPVLQTSTPTSGLLQVSK S 117.0 MS HTP None human T cells 29351928 None
5917 APGYPSSPVTTASGTTLR T 15 2527.0 MS HTP None human HeLa cells 31373491 None
6107 APGYPSSPVTTASGTTLR T 10 2522.0 MS HTP None human HeLa cells 31373491 None
6209 AVLQSMSGR S 7 1286.0 MS HTP None human HeLa cells 31373491 None
10004594 ESTAPAPESITLHDYTTQPASQEQPAQPVLQTSTPTSGLLQVSK S 43 123 MS HTP None human T cells 29351928 None
10019702 171 MS HTP None human HeLa cells 34161081 None
10021163 171 MS HTP None human HeLa cells 34161081 None
10021739 171 MS HTP None human HeLa cells 34161081 None
10023365 APPSSSVTGAHVAQIQAQGITSTAQPLVAGTANGGK S 7 169 MS HTP None human HeLa cells 34846842 None
10024537 2522 MS HTP None human colorectal cancer (CRC) cell lines 35254053 None
10025308 ESTAPAPESITLHDYTTQPASQEQPAQPVLQTSTPTSGLLQVSK T 34 114 MS HTP None human THP1 cells 32938750 None
10025309 ESTAPAPESITLHDYTTQPASQEQPAQPVLQTSTPTSGLLQVSK S 43 123 MS HTP None human THP1 cells 32938750 None
10027099 APGYPSSPVTTASGTTLR S 7 2519 MS HTP None human HeLa cells 35254053 None
10027102 APPSSSVTGAHVAQIQAQGITSTAQPLVAGTANGGK T 8 171 MS HTP None human HeLa cells 35254053 None
10027591 APGYPSSPVTTASGTTLR T 11 2523 MS HTP None human HeLa cells 35254053 None
10027767 APGYPSSPVTTASGTTLR T 10 2522 MS HTP None human HeLa cells 35254053 None
10027999 GSAPAGNPGATGPPLKPAVTLTSTPTQGESK S 2 256 MS HTP None human HeLa cells 35254053 None
10028930 APPSSSVTGAHVAQIQAQGITSTAQPLVAGTANGGK T 21 184 MS HTP None human HeLa cells 35254053 None
10031189 APGYPSSPVTTASGTTLR T 10 2522 MS HTP None human SW620 cells 35254053 None
10031379 GSAPAGNPGATGPPLKPAVTLTSTPTQGESK S 2 256 MS HTP None human SW620 cells 35254053 None
10031991 T 2522 MS HTP None human SW480 cells, SW620 cells 35254053 None