O-GlcNAc Database

Details for Accession #: Q86UE4

Protein Sequence

>sp|Q86UE4|LYRIC_HUMAN Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2
MAARSWQDEL AQQAEEGSAR LREMLSVGLG FLRTELGLDL GLEPKRYPGW VILVGTGALG LLLLFLLGYG WAAACAGARK KRRSPPRKRE EAAAVPAAAP 
DDLALLKNLR SEEQKKKNRK KLSEKPKPNG RTVEVAEGEA VRTPQSVTAK QPPEIDKKNE KSKKNKKKSK SDAKAVQNSS RHDGKEVDEG AWETKISHRE 
KRQQRKRDKV LTDSGSLDST IPGIENTITV TTEQLTTASF PVGSKKNKGD SHLNVQVSNF KSGKGDSTLQ VSSGLNENLT VNGGGWNEKS VKLSSQISAG 
EEKWNSVSPA SAGKRKTEPS AWSQDTGDAN TNGKDWGRSW SDRSIFSGIG STAEPVSQST TSDYQWDVSR NQPYIDDEWS GLNGLSSADP NSDWNAPAEE 
WGNWVDEERA SLLKSQEPIP DDQKVSDDDK EKGEGALPTG KSKKKKKKKK KQGEDNSTAQ DTEELEKEIR EDLPVNTSKT RPKQEKAFSL KTISTSDPAE 
VLVKNSQPIK TLPPATSTEP SVILSKSDSD KSSSQVPPIL QETDKSKSNT KQNSVPPSQT KSETSWESPK QIKKKKKARR ET

Peptide Information

ID	Peptide Seq	Site Residue	Position in Peptide	Position in Protein
5921	TISTSDPAEVLVK	T	4	495
10001622				492
10001818				516
10002264				516
10003107				492
10005575	TISTSDPAEVLVK	T	1	492
10005576	TISTSDPAEVLVK	S	3	494
10009440	TISTSDPAEVLVK	S	5	496
10014837	TISTSDPAEVLVK	S	5	496
10024886	TISTSDPAEVLVK	T	4	495
10026848	TISTSDPAEVLVK	T	1	492
10027447	TLPPATSTEPSVILSK	T	1	511
10028268	TISTSDPAEVLVK	T	1	492
10029282	TISTSDPAEVLVK	T	4	495
10029757	TISTSDPAEVLVK	T	1	492
10030265		T		492
10031980	TISTSDPAEVLVK	T	1	492

O-GlcNAcylation Information

ID	Method	Analytical Throughput	Ambiguity	Species	Sample Type	Condition	log2Ratio	P Value	Data Source PMID	Comments
5921	MS	HTP	ambiguous	human	HeLa cells		None		31373491
10001622	MS	HTP	unambiguous	human	HeLa cells	Interphase/Mitosis	None		34161081	The p value was -log10p in original paper.
10001818	MS	HTP	unambiguous	human	HeLa cells	Interphase/Mitosis	None		34161081	The p value was -log10p in original paper.
10002264	MS	HTP	unambiguous	human	HeLa cells	Mitotic exit/Early mitosis	None		34161081	The p value was -log10p in original paper.
10003107	MS	HTP	unambiguous	human	colorectal cancer (CRC) cell lines	SW620 cells/SW480 cells	None	0.001501611	35254053
10005575	MS	HTP	unambiguous	human	HEK 293T cells	glucose-deprived/glucose-sufficient	None		37541260
10005576	MS	HTP	unambiguous	human	HEK 293T cells	glucose-deprived/glucose-sufficient	None		37541260
10009440	MS	HTP	unambiguous	human	brain		None		28657654
10014837	MS	HTP	unambiguous	human	HeLa cells		None		31373491
10024886	MS	HTP	unambiguous	human	Jurkat cells, MCF-7 cells, K562 cells		None		35132862
10026848	MS	HTP	unambiguous	human	HeLa cells		None		35254053
10027447	MS	HTP	unambiguous	human	HeLa cells		None		35254053
10028268	MS	HTP	unambiguous	human	SW480 cells		None		35254053
10029282	MS	HTP	unambiguous	human	SW620 cells		None		35254053
10029757	MS	HTP	unambiguous	human	SW620 cells		None		35254053
10030265	MS	HTP	unambiguous	human	SW480 cells, SW620 cells	SW620/SW480	None	0.001501611	35254053
10031980	MS	HTP	unambiguous	human	HeLa cell nucleus		None		35289036

ID	Peptide Seq	Site Residue	Position in Peptide	Position in Protein	Method	Analytical Throughput	Ambiguity	Species	Sample Type	Data Source PMID	Comments
5921	TISTSDPAEVLVK	T	4	495	MS	HTP	ambiguous	human	HeLa cells	31373491
10001622				492	MS	HTP	unambiguous	human	HeLa cells	34161081	The p value was -log10p in original paper.
10001818				516	MS	HTP	unambiguous	human	HeLa cells	34161081	The p value was -log10p in original paper.
10002264				516	MS	HTP	unambiguous	human	HeLa cells	34161081	The p value was -log10p in original paper.
10003107				492	MS	HTP	unambiguous	human	colorectal cancer (CRC) cell lines	35254053
10005575	TISTSDPAEVLVK	T	1	492	MS	HTP	unambiguous	human	HEK 293T cells	37541260
10005576	TISTSDPAEVLVK	S	3	494	MS	HTP	unambiguous	human	HEK 293T cells	37541260
10009440	TISTSDPAEVLVK	S	5	496	MS	HTP	unambiguous	human	brain	28657654
10014837	TISTSDPAEVLVK	S	5	496	MS	HTP	unambiguous	human	HeLa cells	31373491
10024886	TISTSDPAEVLVK	T	4	495	MS	HTP	unambiguous	human	Jurkat cells, MCF-7 cells, K562 cells	35132862