Details for Accession #: Q14676

Protein Sequence

>sp|Q14676|MDC1_HUMAN Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3
MEDTQAIDWDVEEEEETEQSSESLRCNVEPVGRLHIFSGAHGPEKDFPLHLGKNVVGRMP
DCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQILRPPKVLSPGVSHRLRDQEL
ILFADLLCQYHRLDVSLPFVSRGPLTVEETPRVQGETQPQRLLLAEDSEEEVDFLSERRM
VKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSDTDVEEGQQPATEEASSAARRG
ATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAGNGVVPAGVILERSQPPGEDSD
TDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIPATPVVIPMKKRKIFHGVGTRG
PGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMVINSDTDDEEEVSAALTLAHLK
ESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEEEELPVENREAVLKDHTKIRAL
VRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTVDINTQVEKEVPPGSAIIHIKK
HQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCETDAEEGTSLTASVVADVRKSQL
PAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLPISRENLTDLVVDTDTLGESTQ
PQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQATQCFLENQGLEAVQSMEDEPTQ
AFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRESEDSETQPFDTHLEAYGPCLS
PPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKETAERVGPERGPLERETEKLLP
ERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASPERDRESLKVEIETSEEI
QEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQRGEPEGGSQDQKG
QASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRI
RAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRK
TRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPK
PTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPE
TVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPV
TSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVK
TPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTE
QPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRS
SVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA
STDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRT
NRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPH
PTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQ
SKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHK
PCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFT
PELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPK
PGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTGVVDARGERAVLALGGSLAGSA
AEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFLPPDEYVVTDPEQEKNFG
FSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVI
TCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAFVLSPLEMSST

Peptide Information

ID Peptide Seq Site Residue Position in Peptide Position in Protein
10009133 LEPSTSTDQPVTPEPTSQATR S 4 1417
10009134 LEPSTSTDQPVTPEPTSQATR S 6 1419
10009672 TPESIVPIAPELQPSTSR S 17 1583
10012231 MTPFPATSAAPEPHPSTSTAQPVTPKPTSQATR S 18 1132
10017516 LEPSTSTDQPVTPEPTSQATR S 4 1417
10017517 LEPSTSTDQPVTPEPTSQATR S 6 1419
10019774 1337
10019838 1132
10026062 MTPFPATSAAPEPHPSTSTAQPVTPKPTSQATR T 24 1138
10027058 MTPFPATSAAPEPHPSTSTAQPVTPKPTSQATR S 18 1132
10027511 MTPFPATSAAPEPHPSTSTAQPVTPKPTSQATR T 19 1133
10027946 MTPFPATSAAPEPHPSTSTAQPVTPK T 2 1116
10028513 TPESIVPIAPELQPSTSR S 17 1583
10028666 MTPFPATSAAPEPHPSTSTAQPVTPK S 18 1132
10028878 TPETVVPTAPELQISTSTDQPVTPKPTSR S 17 1337
10031041 TPESIVPIAPELQPSTSR T 16 1582
10032657 MTPFPATSAAPEPHPSTSTAQPVTPK T 2 1116
10032658 MTPFPATSAAPEPHPSTSTAQPVTPK T 24 1138
10032837 MTPFPATSAAPEPHPSTSTAQPVTPK S 16 1130
10034558 MTPFPATSAAPEPHPSTSTAQPVTPKPTSQATR S 1132

O-GlcNAcylation Information

ID Method Analytical Throughput Ambiguity Species Sample Type Data Source PMID Comments
10009133 MS HTP None human HEK 293T cells 30620550 None
10009134 MS HTP None human HEK 293T cells 30620550 None
10009672 MS HTP None human HEK 293T cells 30620550 None
10012231 MS HTP None human MCF-7 cells 32574038 None
10017516 MS HTP None human HEK 293T cells 30620550 None
10017517 MS HTP None human HEK 293T cells 30620550 None
10019774 MS HTP None human HeLa cells 34161081 None
10019838 MS HTP None human HeLa cells 34161081 None
10026062 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10027058 MS HTP None human HeLa cells 35254053 None
10027511 MS HTP None human HeLa cells 35254053 None
10027946 MS HTP None human HeLa cells 35254053 None
10028513 MS HTP None human HeLa cells 35254053 None
10028666 MS HTP None human HeLa cells 35254053 None
10028878 MS HTP None human HeLa cells 35254053 None
10031041 MS HTP None human SW620 cells 35254053 None
10032657 MS HTP None human HeLa cell nucleus 35289036 None
10032658 MS HTP None human HeLa cell nucleus 35289036 None
10032837 MS HTP None human HeLa cell nucleus 35289036 None
10034558 MS HTP None human MCF-7 cells 35513511 None
ID Peptide Seq Site Residue Position in Peptide Position in Protein Method Analytical Throughput Ambiguity Species Sample Type Data Source PMID Comments
10009133 LEPSTSTDQPVTPEPTSQATR S 4 1417 MS HTP None human HEK 293T cells 30620550 None
10009134 LEPSTSTDQPVTPEPTSQATR S 6 1419 MS HTP None human HEK 293T cells 30620550 None
10009672 TPESIVPIAPELQPSTSR S 17 1583 MS HTP None human HEK 293T cells 30620550 None
10012231 MTPFPATSAAPEPHPSTSTAQPVTPKPTSQATR S 18 1132 MS HTP None human MCF-7 cells 32574038 None
10017516 LEPSTSTDQPVTPEPTSQATR S 4 1417 MS HTP None human HEK 293T cells 30620550 None
10017517 LEPSTSTDQPVTPEPTSQATR S 6 1419 MS HTP None human HEK 293T cells 30620550 None
10019774 1337 MS HTP None human HeLa cells 34161081 None
10019838 1132 MS HTP None human HeLa cells 34161081 None
10026062 MTPFPATSAAPEPHPSTSTAQPVTPKPTSQATR T 24 1138 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10027058 MTPFPATSAAPEPHPSTSTAQPVTPKPTSQATR S 18 1132 MS HTP None human HeLa cells 35254053 None
10027511 MTPFPATSAAPEPHPSTSTAQPVTPKPTSQATR T 19 1133 MS HTP None human HeLa cells 35254053 None
10027946 MTPFPATSAAPEPHPSTSTAQPVTPK T 2 1116 MS HTP None human HeLa cells 35254053 None
10028513 TPESIVPIAPELQPSTSR S 17 1583 MS HTP None human HeLa cells 35254053 None
10028666 MTPFPATSAAPEPHPSTSTAQPVTPK S 18 1132 MS HTP None human HeLa cells 35254053 None
10028878 TPETVVPTAPELQISTSTDQPVTPKPTSR S 17 1337 MS HTP None human HeLa cells 35254053 None
10031041 TPESIVPIAPELQPSTSR T 16 1582 MS HTP None human SW620 cells 35254053 None
10032657 MTPFPATSAAPEPHPSTSTAQPVTPK T 2 1116 MS HTP None human HeLa cell nucleus 35289036 None
10032658 MTPFPATSAAPEPHPSTSTAQPVTPK T 24 1138 MS HTP None human HeLa cell nucleus 35289036 None
10032837 MTPFPATSAAPEPHPSTSTAQPVTPK S 16 1130 MS HTP None human HeLa cell nucleus 35289036 None
10034558 MTPFPATSAAPEPHPSTSTAQPVTPKPTSQATR S 1132 MS HTP None human MCF-7 cells 35513511 None