Details for Accession #: Q03164

Protein Sequence

>sp|Q03164|KMT2A_HUMAN Histone-lysine N-methyltransferase 2A OS=Homo sapiens OX=9606 GN=KMT2A PE=1 SV=5
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAV
AAAAAAAGSSGAGVPGGAAAASAASSSSASSSSSSSSSASSGPALLRVGPGFDAALQVSA
AIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKD
ISELPKGNKEDSLKKIKRTPSATFQQATKIKKLRAGKLSPLKSKFKTGKLQIGRKGVQIV
RRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSR
IIKTPRRFIEDEDYDPPIKIARLESTPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSS
SPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPAS
TAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPED
VGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSL
SISVSPLATSALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFT
PGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKI
LIKKGRGNLEKTNLDLGPTAPSLEKEKTLCLSTPSSSTVKHSTSSIGSMLAQADKLPMTD
KRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKA
PQEPPVKKGRRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWM
PSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVP
KTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPPVNKQENAGTLNIL
STLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASS
GHVEFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNK
CRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCA
KLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYT
CVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESI
PSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINS
DGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDH
NYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPE
LNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKN
VHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDL
IKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDC
EDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRPPVVEPDINSTVEHDENRTIAHSPT
SFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTPSYSPTQRSPGCR
PLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRIMSPMRTGNTYS
RNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHL
DGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTS
RELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVK
TLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNL
KPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTV
KVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSC
QDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSY
GEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASH
NLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPED
AGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNL
LDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEG
LGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPT
VPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMD
ADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQIS
NAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTS
VLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNP
PSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTP
SNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAP
LLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPG
HVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAI
TAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRDLDSASGPQV
SNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKT
KRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGTPGAEAEQQDTASVEQSS
QKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESI
TEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRML
GILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARAEVHLRKSAFDMFNF
LASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHG
RGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGN
AARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCNCG
AKKCRKFLN

Peptide Information

ID Peptide Seq Site Residue Position in Peptide Position in Protein
3277 EKVVGEDVATSSSAK S 925.0
3278 EKVVGEDVATSSSAK S 926.0
3279 LAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHR S 3241.0
3280 LAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHR S 3267.0
3281 LAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHR S 3273.0
3282 LSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESAEK S 764.0
3283 LSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESAEK S 777.0
3284 LSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESAEK S 778.0
3285 LSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESAEK S 781.0
3286 LSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESAEK S 783.0
3287 NVVSMQTTTTPTSSASVPGHVTL T 3353.0
3288 SILREPTFRWTSLK T 616.0
3289 TTPSEPKK S 1325.0
10004672 LAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHR S 5 3238
10004698 LSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESAEK S 14 775
10004852 EDSPELNPPPGIEDNR S 3 1858
10007477 RTPSATFQQATKIK T 259
10007478 SFGSRTTKK S 540
10012218 YVPNSTDSPGPSQISNAAVQTTPPHLKPATEK S 15 3060
10024363 3050
10028958 YVPNSTDSPGPSQISNAAVQTTPPHLKPATEK T 6 3051
10029467 YVPNSTDSPGPSQISNAAVQTTPPHLKPATEK S 5 3050
10030131 TDLSTTVATPSSGLK T 6 3210
10031010 YVPNSTDSPGPSQISNAAVQTTPPHLKPATEK S 5 3050
10031830 S 3050
10033169 LAPQVHNTTSR S 10 2340

O-GlcNAcylation Information

ID Method Analytical Throughput Ambiguity Species Sample Type Data Source PMID Comments
3277 MS HTP None human T cells 29351928 None
3278 MS HTP None human T cells 29351928 None
3279 MS HTP None human T cells 29351928 None
3280 MS HTP None human T cells 29351928 None
3281 MS HTP None human T cells 29351928 None
3282 MS HTP None human T cells 29351928 None
3283 MS HTP None human T cells 29351928 None
3284 MS HTP None human T cells 29351928 None
3285 MS HTP None human T cells 29351928 None
3286 MS HTP None human T cells 29351928 None
3287 MS HTP None human T cells 29351928 None
3288 MS HTP None human T cells 29351928 None
3289 MS HTP None human T cells 29351928 None
10004672 MS HTP None human T cells 29351928 None
10004698 MS HTP None human T cells 29351928 None
10004852 MS HTP None human T cells 29351928 None
10007477 MS HTP None human HeLa cells 30379171 None
10007478 MS HTP None human HeLa cells 30379171 None
10012218 MS HTP None human MCF-7 cells 32574038 None
10024363 MS HTP None human colorectal cancer (CRC) cell lines 35254053 None
10028958 MS HTP None human HeLa cells 35254053 None
10029467 MS HTP None human SW480 cells 35254053 None
10030131 MS HTP None human SW480 cells 35254053 None
10031010 MS HTP None human SW620 cells 35254053 None
10031830 MS HTP None human SW480 cells, SW620 cells 35254053 None
10033169 MS HTP None human HeLa cell nucleus 35289036 None
ID Peptide Seq Site Residue Position in Peptide Position in Protein Method Analytical Throughput Ambiguity Species Sample Type Data Source PMID Comments
3277 EKVVGEDVATSSSAK S 925.0 MS HTP None human T cells 29351928 None
3278 EKVVGEDVATSSSAK S 926.0 MS HTP None human T cells 29351928 None
3279 LAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHR S 3241.0 MS HTP None human T cells 29351928 None
3280 LAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHR S 3267.0 MS HTP None human T cells 29351928 None
3281 LAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHR S 3273.0 MS HTP None human T cells 29351928 None
3282 LSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESAEK S 764.0 MS HTP None human T cells 29351928 None
3283 LSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESAEK S 777.0 MS HTP None human T cells 29351928 None
3284 LSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESAEK S 778.0 MS HTP None human T cells 29351928 None
3285 LSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESAEK S 781.0 MS HTP None human T cells 29351928 None
3286 LSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESAEK S 783.0 MS HTP None human T cells 29351928 None
3287 NVVSMQTTTTPTSSASVPGHVTL T 3353.0 MS HTP None human T cells 29351928 None
3288 SILREPTFRWTSLK T 616.0 MS HTP None human T cells 29351928 None
3289 TTPSEPKK S 1325.0 MS HTP None human T cells 29351928 None
10004672 LAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHR S 5 3238 MS HTP None human T cells 29351928 None
10004698 LSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESAEK S 14 775 MS HTP None human T cells 29351928 None
10004852 EDSPELNPPPGIEDNR S 3 1858 MS HTP None human T cells 29351928 None
10007477 RTPSATFQQATKIK T 259 MS HTP None human HeLa cells 30379171 None
10007478 SFGSRTTKK S 540 MS HTP None human HeLa cells 30379171 None
10012218 YVPNSTDSPGPSQISNAAVQTTPPHLKPATEK S 15 3060 MS HTP None human MCF-7 cells 32574038 None
10024363 3050 MS HTP None human colorectal cancer (CRC) cell lines 35254053 None
10028958 YVPNSTDSPGPSQISNAAVQTTPPHLKPATEK T 6 3051 MS HTP None human HeLa cells 35254053 None
10029467 YVPNSTDSPGPSQISNAAVQTTPPHLKPATEK S 5 3050 MS HTP None human SW480 cells 35254053 None
10030131 TDLSTTVATPSSGLK T 6 3210 MS HTP None human SW480 cells 35254053 None
10031010 YVPNSTDSPGPSQISNAAVQTTPPHLKPATEK S 5 3050 MS HTP None human SW620 cells 35254053 None
10031830 S 3050 MS HTP None human SW480 cells, SW620 cells 35254053 None
10033169 LAPQVHNTTSR S 10 2340 MS HTP None human HeLa cell nucleus 35289036 None