Details for Accession #: P49336

Protein Sequence

>sp|P49336|CDK8_HUMAN Cyclin-dependent kinase 8 OS=Homo sapiens OX=9606 GN=CDK8 PE=1 SV=1
MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGIS
MSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKP
VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
IKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKH
KVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLT
EEEPDDKGDKKNQQQQQGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTS
DYQRSNPHAAYPNPGPSTSQPQSSMGYSATSQQPPQYSHQTHRY

Peptide Information

ID Peptide Seq Site Residue Position in Peptide Position in Protein
10005782 GPPLKKVRVVPPTTTSGGLIMTSDYQRSNPH S 413
10005783 TQGPPLKKVRVVPPTTTSGGLIMTSDYQRSN T 411
10005784 QGPPLKKVRVVPPTTTSGGLIMTSDYQRSNP T 412
10009840 VVPPTTTSGGLIMTSDYQR S 8 413
10009841 VVPPTTTSGGLIMTSDYQR T 6 411
10017334 VVPPTTTSGGLIMTSDYQR T 6 411
10017335 VVPPTTTSGGLIMTSDYQR T 6 411
10017336 VVPPTTTSGGLIMTSDYQR S 8 413
10019705 410
10020255 412
10020318 411
10020929 412
10021534 412
10021971 411
10024320 411
10024838 VVPPTTTSGGLIMTSDYQR T 6 411
10025897 VVPPTTTSGGLIMTSDYQR T 5 410
10025898 VVPPTTTSGGLIMTSDYQR T 7 412
10026903 VVPPTTTSGGLIMTSDYQR T 7 412
10027018 VVPPTTTSGGLIMTSDYQR T 6 411
10027821 VVPPTTTSGGLIMTSDYQR T 5 410
10029376 VVPPTTTSGGLIMTSDYQR T 6 411
10029377 VVPPTTTSGGLIMTSDYQR T 7 412
10029889 VVPPTTTSGGLIMTSDYQR T 5 410
10030359 VVPPTTTSGGLIMTSDYQR T 6 411
10030360 VVPPTTTSGGLIMTSDYQR T 7 412
10031259 VVPPTTTSGGLIMTSDYQR T 5 410
10031787 T 411
10032597 VVPPTTTSGGLIMTSDYQR T 5 410
10033088 VVPPTTTSGGLIMTSDYQR S 8 413
10033089 VVPPTTTSGGLIMTSDYQR T 7 412
10034968 VVPPTTTSGGLIMTSDYQR T 6 411

O-GlcNAcylation Information

ID Method Analytical Throughput Ambiguity Species Sample Type Data Source PMID Comments
10005782 MS HTP None human HeLa cells 30059200 None
10005783 MS HTP None human HeLa cells 30059200 None
10005784 MS HTP None human HeLa cells 30059200 None
10009840 MS HTP None human HEK 293T cells 30620550 None
10009841 MS HTP None human HEK 293T cells 30620550 None
10017334 MS HTP None human HepG2 cells 30620550 None
10017335 MS HTP None human HEK 293T cells 30620550 None
10017336 MS HTP None human HEK 293T cells 30620550 None
10019705 MS HTP None human HeLa cells 34161081 None
10020255 MS HTP None human HeLa cells 34161081 None
10020318 MS HTP None human HeLa cells 34161081 None
10020929 MS HTP None human HeLa cells 34161081 None
10021534 MS HTP None human HeLa cells 34161081 None
10021971 MS HTP None human HeLa cells 34161081 None
10024320 MS HTP None human colorectal cancer (CRC) cell lines 35254053 None
10024838 MS HTP None human THP1 cells 32938750 None
10025897 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10025898 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10026903 MS HTP None human HeLa cells 35254053 None
10027018 MS HTP None human HeLa cells 35254053 None
10027821 MS HTP None human HeLa cells 35254053 None
10029376 MS HTP None human SW480 cells 35254053 None
10029377 MS HTP None human SW480 cells 35254053 None
10029889 MS HTP None human SW480 cells 35254053 None
10030359 MS HTP None human SW620 cells 35254053 None
10030360 MS HTP None human SW620 cells 35254053 None
10031259 MS HTP None human SW620 cells 35254053 None
10031787 MS HTP None human SW480 cells, SW620 cells 35254053 None
10032597 MS HTP None human HeLa cell nucleus 35289036 None
10033088 MS HTP None human HeLa cell nucleus 35289036 None
10033089 MS HTP None human HeLa cell nucleus 35289036 None
10034968 MS HTP None human Jurkat cells 35705054 None
ID Peptide Seq Site Residue Position in Peptide Position in Protein Method Analytical Throughput Ambiguity Species Sample Type Data Source PMID Comments
10005782 GPPLKKVRVVPPTTTSGGLIMTSDYQRSNPH S 413 MS HTP None human HeLa cells 30059200 None
10005783 TQGPPLKKVRVVPPTTTSGGLIMTSDYQRSN T 411 MS HTP None human HeLa cells 30059200 None
10005784 QGPPLKKVRVVPPTTTSGGLIMTSDYQRSNP T 412 MS HTP None human HeLa cells 30059200 None
10009840 VVPPTTTSGGLIMTSDYQR S 8 413 MS HTP None human HEK 293T cells 30620550 None
10009841 VVPPTTTSGGLIMTSDYQR T 6 411 MS HTP None human HEK 293T cells 30620550 None
10017334 VVPPTTTSGGLIMTSDYQR T 6 411 MS HTP None human HepG2 cells 30620550 None
10017335 VVPPTTTSGGLIMTSDYQR T 6 411 MS HTP None human HEK 293T cells 30620550 None
10017336 VVPPTTTSGGLIMTSDYQR S 8 413 MS HTP None human HEK 293T cells 30620550 None
10019705 410 MS HTP None human HeLa cells 34161081 None
10020255 412 MS HTP None human HeLa cells 34161081 None
10020318 411 MS HTP None human HeLa cells 34161081 None
10020929 412 MS HTP None human HeLa cells 34161081 None
10021534 412 MS HTP None human HeLa cells 34161081 None
10021971 411 MS HTP None human HeLa cells 34161081 None
10024320 411 MS HTP None human colorectal cancer (CRC) cell lines 35254053 None
10024838 VVPPTTTSGGLIMTSDYQR T 6 411 MS HTP None human THP1 cells 32938750 None
10025897 VVPPTTTSGGLIMTSDYQR T 5 410 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10025898 VVPPTTTSGGLIMTSDYQR T 7 412 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10026903 VVPPTTTSGGLIMTSDYQR T 7 412 MS HTP None human HeLa cells 35254053 None
10027018 VVPPTTTSGGLIMTSDYQR T 6 411 MS HTP None human HeLa cells 35254053 None
10027821 VVPPTTTSGGLIMTSDYQR T 5 410 MS HTP None human HeLa cells 35254053 None
10029376 VVPPTTTSGGLIMTSDYQR T 6 411 MS HTP None human SW480 cells 35254053 None
10029377 VVPPTTTSGGLIMTSDYQR T 7 412 MS HTP None human SW480 cells 35254053 None
10029889 VVPPTTTSGGLIMTSDYQR T 5 410 MS HTP None human SW480 cells 35254053 None
10030359 VVPPTTTSGGLIMTSDYQR T 6 411 MS HTP None human SW620 cells 35254053 None
10030360 VVPPTTTSGGLIMTSDYQR T 7 412 MS HTP None human SW620 cells 35254053 None
10031259 VVPPTTTSGGLIMTSDYQR T 5 410 MS HTP None human SW620 cells 35254053 None
10031787 T 411 MS HTP None human SW480 cells, SW620 cells 35254053 None
10032597 VVPPTTTSGGLIMTSDYQR T 5 410 MS HTP None human HeLa cell nucleus 35289036 None
10033088 VVPPTTTSGGLIMTSDYQR S 8 413 MS HTP None human HeLa cell nucleus 35289036 None
10033089 VVPPTTTSGGLIMTSDYQR T 7 412 MS HTP None human HeLa cell nucleus 35289036 None
10034968 VVPPTTTSGGLIMTSDYQR T 6 411 MS HTP None human Jurkat cells 35705054 None