Details for Accession #: P24928

Protein Sequence

>sp|P24928|RPB1_HUMAN DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2
MHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMDP
RQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVD
SNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKG
HGGCGRYQPRIRRSGLELYAEWKHVNEDSQEKKILLSPERVHEIFKRISDEECFVLGMEP
RYARPEWMIVTVLPVPPLSVRPAVVMQGSARNQDDLTHKLADIVKINNQLRRNEQNGAAA
HVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKRVD
FSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKYII
RDNGDRIDLRFHPKPSDLHLQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPWS
TFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQD
TLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHI
NCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLVHISYLEM
GHDITRLFYSNIQTVINNWLLIEGHTIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKA
HNNELEPTPGNTLRQTFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKIN
ISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHA
MGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGES
VEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQNELEREFERMR
EDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKL
VIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAI
AHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKKPKTPSLT
VFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMP
DFDVARISPWLLRVELDRKHMTDRKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIR
IMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKI
IITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALER
ELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVLM
EAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTG
MFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPG
YSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSP
SYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP
TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS
YSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPT
SPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPASPKYTPTSPSYSPSSPEYTPTSPKY
SPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTS
PKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPDDSDEEN

Peptide Information

ID Peptide Seq Site Residue Position in Peptide Position in Protein
2195 SPSVGSGMTPGAAGFSPSAASDASGF S 3 1534.0
5788 YSPTSPTYSPTSPVYTPTSPK T 11 1898.0
5998 YSPTSPTYSPTSPVYTPTSPK T 7 1894.0
6042 YTPTSPSYSPSSPEYTPTSPK S 9 1847.0
6157 YSPTSPTYSPTSPVYTPTSPK S 5 1892.0
10000411 YTPQSPTYTPSSPSYSPSSPSYSPASPK S 12 1822
10000412 YSPTSPTYSPTSPVYTPTSPK S 2 1889
10015006 YSPTSPS S 5
10015007 YSPTSPS S 7

O-GlcNAcylation Information

ID Method Analytical Throughput Ambiguity Species Sample Type Data Source PMID Comments
2195 MS HTP None human T cells 29351928 None
5788 MS HTP None human HeLa cells 31373491 None
5998 MS HTP None human HeLa cells 31373491 None
6042 MS HTP None human HeLa cells 31373491 None
6157 MS HTP None human HeLa cells 31373491 None
10000411 MS LTP None human 27129214 None
10000412 MS LTP None human 27129214 None
10015006 Site-directed mutagenesis LTP None human HeLa cells 22605332 None
10015007 Site-directed mutagenesis LTP None human HeLa cells 22605332 None
ID Peptide Seq Site Residue Position in Peptide Position in Protein Method Analytical Throughput Ambiguity Species Sample Type Data Source PMID Comments
2195 SPSVGSGMTPGAAGFSPSAASDASGF S 3 1534.0 MS HTP None human T cells 29351928 None
5788 YSPTSPTYSPTSPVYTPTSPK T 11 1898.0 MS HTP None human HeLa cells 31373491 None
5998 YSPTSPTYSPTSPVYTPTSPK T 7 1894.0 MS HTP None human HeLa cells 31373491 None
6042 YTPTSPSYSPSSPEYTPTSPK S 9 1847.0 MS HTP None human HeLa cells 31373491 None
6157 YSPTSPTYSPTSPVYTPTSPK S 5 1892.0 MS HTP None human HeLa cells 31373491 None
10000411 YTPQSPTYTPSSPSYSPSSPSYSPASPK S 12 1822 MS LTP None human 27129214 None
10000412 YSPTSPTYSPTSPVYTPTSPK S 2 1889 MS LTP None human 27129214 None
10015006 YSPTSPS S 5 Site-directed mutagenesis LTP None human HeLa cells 22605332 None
10015007 YSPTSPS S 7 Site-directed mutagenesis LTP None human HeLa cells 22605332 None