Details for Accession #: P22681


Protein Sequence

>sp|P22681|CBL_HUMAN E3 ubiquitin-protein ligase CBL OS=Homo sapiens OX=9606 GN=CBL PE=1 SV=2
MAGNVKKSSGAGGGSGSGGSGSGGLIGLMKDAFQPHHHHHHHLSPHPPGTVDKKMVEKCW
KLMDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRTILSRYEGKMETLGENEYFRVFME
NLMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFR
ITKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFE
FDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRL
GQWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDH
IKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFCR
CEIKGTEPIVVDPFDPRGSGSLLRQGAEGAPSPNYDDDDDERADDTLFMMKELAGAKVER
PPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLR
DLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPV
SAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSPLVGPECD
HPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDTEYMTPSSRPLRPLDTSQSSRAC
DCDQQIDSCTYEAMYNIQSQAPSITESSTFGEGNLAAAHANTGPEESENEDDGYDVPKPP
VPAVLARRTLSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPKPFPRRINSERKAGSC
QQGSGPAASAATASPQLSSEIENLMSQGYSYQDIQKALVIAQNNIEMAKNILREFVSISS
PAHVAT

Peptide Information

ID Peptide Seq Site Residue Position in Peptide Position in Protein
2177 GDSWLPRPIPKVPVSAPSSSDPW S 3 589.0
2179 LPRPIPKVPVSAPSSSDPW S 14 604.0
2180 LPRPIPKVPVSAPSSSDPW S 15 605.0
2181 STIDLTCNDYISVFEFDIFTR T 20 245.0
2182 VPVSAPSSSDPWTGR S 9 606.0
2183 VPVSAPSSSDPWTGR T 13 610.0
5656 VPVSAPSSSDPWTGR S 8 605.0
5657 VPVSAPSSSDPWTGR S 9 606.0
5658 VPVSAPSSSDPWTGR S 4 601.0
5659 VPVSAPSSSDPWTGR S 7 604.0
5954 HSLPFSLPSQMEPRPDVPR S 9 626.0
10002808 VPVSAPSSSDPWTGR S 4 601
10003767 VPVSAPSSSDPWTGR S 4 601
10004824 VPVSAPSSSDPWTGR S 4 601
10005714 LGDSWLPRPIPKVPVSAPSSSDPWTGRELTN S 601
10007284 VPVSAPSSSDPWTGR S 601
10009805 VPVSAPSSSDPWTGR S 4 601
10010654 HSLPFSLPSQMEPRPDVPR S 6 623
10010807 VPVSAPSSSDPWTGR S 4 601
10011775 VPVSAPSSSDPWTGR S 9 606
10011776 VPVSAPSSSDPWTGR T 13 610
10012168 VPVSAPSSSDPWTGR S 7 604
10012169 VPVSAPSSSDPWTGR S 8 605
10015239 VPVSAPSSSDPWTGR S 601
10016638 VPVSAPSSSDPWTGR S 4 601
10017401 VPVSAPSSSDPWTGR S 4 601
10017402 VPVSAPSSSDPWTGR S 4 601
10017810 VPVSAPSSSDPWTGR S 4 601
10018901 601
10022162 601
10024024 601
10024799 VPVSAPSSSDPWTGR S 4 601
10025833 VCVPSSASALGTASK S 6 512
10025834 VPVSAPSSSDPWTGR S 7 604
10025835 VPVSAPSSSDPWTGR S 9 606
10025836 VPVSAPSSSDPWTGRELTNR S 4 601
10026584 VPVSAPSSSDPWTGR S 4 601
10029867 VPVSAPSSSDPWTGR S 4 601
10030326 VPVSAPSSSDPWTGR S 4 601
10031504 S 601
10033682 VPVSAPSSSDPWTGR S 601
10034755 VPVSAPSSSDPWTGR S 4 601
10034958 VPVSAPSSSDPWTGR S 4 601
10035520 VPVSAPSSSDPWTGR S 4 601

O-GlcNAcylation Information

ID Method Analytical Throughput Ambiguity Species Sample Type Data Source PMID Comments
2177 MS HTP None human T cells 29351928 None
2179 MS HTP None human T cells 29351928 None
2180 MS HTP None human T cells 29351928 None
2181 MS HTP None human T cells 29351928 None
2182 MS HTP None human T cells 29351928 None
2183 MS HTP None human T cells 29351928 None
5656 MS HTP None human HeLa cells 31373491 None
5657 MS HTP None human HeLa cells 31373491 None
5658 MS HTP None human HeLa cells 31373491 None
5659 MS HTP None human HeLa cells 31373491 None
5954 MS HTP None human HeLa cells 31373491 None
10002808 MS HTP None human HEK 293 cells 23301498 None
10003767 MS HTP None human brain 28657654 None
10004824 MS HTP None human T cells 29351928 None
10005714 MS HTP None human HeLa cells 30059200 None
10007284 MS HTP None human HeLa cells 30379171 None
10009805 MS HTP None human HEK 293T cells 30620550 None
10010654 MS HTP None human HeLa cells 31373491 None
10010807 MS HTP None human HeLa cells 31492838 None
10011775 MS HTP None human MCF-7 cells 32574038 None
10011776 MS HTP None human MCF-7 cells 32574038 None
10012168 MS HTP None human MCF-7 cells 32574038 None
10012169 MS HTP None human MCF-7 cells 32574038 None
10015239 MS HTP None human Hela cells 29237092 None
10016638 MS HTP None human HeLa cells 30059200 None
10017401 MS HTP None human HepG2 cells 30620550 None
10017402 MS HTP None human HEK 293T cells 30620550 None
10017810 MS HTP None human HEK 293T cells 30620550 None
10018901 MS HTP None human HeLa cells 34161081 None
10022162 MS HTP None human HeLa cells 34161081 None
10024024 MS HTP None human colorectal cancer (CRC) cell lines 35254053 None
10024799 MS HTP None human THP1 cells 32938750 None
10025833 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10025834 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10025835 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10025836 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10026584 MS HTP None human HeLa cells 35254053 None
10029867 MS HTP None human SW480 cells 35254053 None
10030326 MS HTP None human SW620 cells 35254053 None
10031504 MS HTP None human SW480 cells, SW620 cells 35254053 None
10033682 MS HTP None human MCF-7 cells 35513511 None
10034755 MS HTP None human Jurkat cells 35705054 None
10034958 MS HTP None human Jurkat cells 35705054 None
10035520 MS HTP None human PANC-1 cells 36240223 None

ID Peptide Seq Site Residue Position in Peptide Position in Protein Method Analytical Throughput Ambiguity Species Sample Type Data Source PMID Comments
2177 GDSWLPRPIPKVPVSAPSSSDPW S 3 589.0 MS HTP None human T cells 29351928 None
2179 LPRPIPKVPVSAPSSSDPW S 14 604.0 MS HTP None human T cells 29351928 None
2180 LPRPIPKVPVSAPSSSDPW S 15 605.0 MS HTP None human T cells 29351928 None
2181 STIDLTCNDYISVFEFDIFTR T 20 245.0 MS HTP None human T cells 29351928 None
2182 VPVSAPSSSDPWTGR S 9 606.0 MS HTP None human T cells 29351928 None
2183 VPVSAPSSSDPWTGR T 13 610.0 MS HTP None human T cells 29351928 None
5656 VPVSAPSSSDPWTGR S 8 605.0 MS HTP None human HeLa cells 31373491 None
5657 VPVSAPSSSDPWTGR S 9 606.0 MS HTP None human HeLa cells 31373491 None
5658 VPVSAPSSSDPWTGR S 4 601.0 MS HTP None human HeLa cells 31373491 None
5659 VPVSAPSSSDPWTGR S 7 604.0 MS HTP None human HeLa cells 31373491 None
5954 HSLPFSLPSQMEPRPDVPR S 9 626.0 MS HTP None human HeLa cells 31373491 None
10002808 VPVSAPSSSDPWTGR S 4 601 MS HTP None human HEK 293 cells 23301498 None
10003767 VPVSAPSSSDPWTGR S 4 601 MS HTP None human brain 28657654 None
10004824 VPVSAPSSSDPWTGR S 4 601 MS HTP None human T cells 29351928 None
10005714 LGDSWLPRPIPKVPVSAPSSSDPWTGRELTN S 601 MS HTP None human HeLa cells 30059200 None
10007284 VPVSAPSSSDPWTGR S 601 MS HTP None human HeLa cells 30379171 None
10009805 VPVSAPSSSDPWTGR S 4 601 MS HTP None human HEK 293T cells 30620550 None
10010654 HSLPFSLPSQMEPRPDVPR S 6 623 MS HTP None human HeLa cells 31373491 None
10010807 VPVSAPSSSDPWTGR S 4 601 MS HTP None human HeLa cells 31492838 None
10011775 VPVSAPSSSDPWTGR S 9 606 MS HTP None human MCF-7 cells 32574038 None
10011776 VPVSAPSSSDPWTGR T 13 610 MS HTP None human MCF-7 cells 32574038 None
10012168 VPVSAPSSSDPWTGR S 7 604 MS HTP None human MCF-7 cells 32574038 None
10012169 VPVSAPSSSDPWTGR S 8 605 MS HTP None human MCF-7 cells 32574038 None
10015239 VPVSAPSSSDPWTGR S 601 MS HTP None human Hela cells 29237092 None
10016638 VPVSAPSSSDPWTGR S 4 601 MS HTP None human HeLa cells 30059200 None
10017401 VPVSAPSSSDPWTGR S 4 601 MS HTP None human HepG2 cells 30620550 None
10017402 VPVSAPSSSDPWTGR S 4 601 MS HTP None human HEK 293T cells 30620550 None
10017810 VPVSAPSSSDPWTGR S 4 601 MS HTP None human HEK 293T cells 30620550 None
10018901 601 MS HTP None human HeLa cells 34161081 None
10022162 601 MS HTP None human HeLa cells 34161081 None
10024024 601 MS HTP None human colorectal cancer (CRC) cell lines 35254053 None
10024799 VPVSAPSSSDPWTGR S 4 601 MS HTP None human THP1 cells 32938750 None
10025833 VCVPSSASALGTASK S 6 512 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10025834 VPVSAPSSSDPWTGR S 7 604 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10025835 VPVSAPSSSDPWTGR S 9 606 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10025836 VPVSAPSSSDPWTGRELTNR S 4 601 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10026584 VPVSAPSSSDPWTGR S 4 601 MS HTP None human HeLa cells 35254053 None
10029867 VPVSAPSSSDPWTGR S 4 601 MS HTP None human SW480 cells 35254053 None
10030326 VPVSAPSSSDPWTGR S 4 601 MS HTP None human SW620 cells 35254053 None
10031504 S 601 MS HTP None human SW480 cells, SW620 cells 35254053 None
10033682 VPVSAPSSSDPWTGR S 601 MS HTP None human MCF-7 cells 35513511 None
10034755 VPVSAPSSSDPWTGR S 4 601 MS HTP None human Jurkat cells 35705054 None
10034958 VPVSAPSSSDPWTGR S 4 601 MS HTP None human Jurkat cells 35705054 None
10035520 VPVSAPSSSDPWTGR S 4 601 MS HTP None human PANC-1 cells 36240223 None