Details for Accession #: P12270

Protein Sequence

>sp|P12270|TPR_HUMAN Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3
MAAVLQQVLERTELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKR
LSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEEL
EAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYRE
KRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQM
NGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKS
NELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLL
SATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRIN
KYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSS
VLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSY
RNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQ
MQLVDSIVRQRDMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPSTSQTVSTPAPVPVI
ESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDF
ASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVR
AENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQ
IEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKE
IATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTS
NVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQD
DKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQN
KYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKD
EVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEIL
RFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHE
ELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGM
LQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKA
EIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRR
YKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENL
QKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAA
KSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREH
QERHLEQRDEPQEPSNKVPEQQRQITLKTTPASGERGIASTSDPPTANIKPTPVVSTPSK
VTAAAMAGNKSTPRASIRPMVTPATVTNPTTTPTATVMPTTQVESQEAMQSEGPVEHVPV
FGSTSGSVRSTSPNVQPSISQPILTVQQQTQATAFVQPTQQSHPQIEPANQELSSNIVEV
VQSSPVERPSTSTAVFGTVSATPSSSLPKRTREEEEDSTIEASDQVSDDTVEMPLPKKLK
SVTPVGTEEEVMAEESTDGEVETQVYNQDSQDSIGEGVTQGDYTPMEDSEETSQSLQIDL
GPLQSDQQTTTSSQDGQGKGDDVIVIDSDDEEEDDDENDGEHEDYEEDEEDDDDDEDDTG
MGDEGEDSNEGTGSADGNDGYEADDAEGGDGTDPGTETEESMGGGEGNHRAADSQNSGEG
NTGAAESSFSQEVSREQQPSSASERQAPRAPQSPRRPPHPLPPRLTIHAPPQELGPPVQR
IQMTRRQSVGRGLQLTPGIGGMQQHFFDDEDRTVPSTPTLVVPHRTDGFAEAIHSPQVAG
VPRFRFGPPEDMPQTSSSHSDLGQLASQGGLGMYETPLFLAHEEESGGRSVPTTPLQVAA
PVTVFTESTTSDASEHASQSVPMVTTSTGTLSTTNETATGDDGDEVFVEAESEGISSEAG
LEIDSQQEEEPVQASDESDLPSTSQDPPSSSSVDTSSSQPKPFRRVRLQTTLRQGVRGRQ
FNRQRGVSHAMGGRGGINRGNIN

Peptide Information

ID Peptide Seq Site Residue Position in Peptide Position in Protein
497 GIASTSDPPTANIKPTPVVSTPSK T 10 1666.0
498 GIASTSDPPTANIKPTPVVSTPSK T 16 1672.0
499 GIASTSDPPTANIKPTPVVSTPSK S 20 1676.0
500 GIASTSDPPTANIKPTPVVSTPSK T 21 1677.0
2061 FGPPEDMPQTSSSHSDLGQLASQGGLGMYETPLFLAHEEESGGR S 22 2187.0
2062 GIASTSDPPTANIKPTPVVSTPSK T 16 1672.0
2063 GIASTSDPPTANIKPTPVVSTPSK T 21 1677.0
2064 GIASTSDPPTANIKPTPVVSTPSK S 23 1679.0
2065 SSNIVEVVQSSPVERPSTSTAVF S 11 1804.0
5531 EQQPSSASER S 8 2063.0
5533 EQQPSSASER S 5 2060.0
5564 GIASTSDPPTANIK S 4 1660.0
5687 GIASTSDPPTANIKPTPVVSTPSK S 20 1676.0
5816 RPSTSQTVSTPAPVPVIESTEAIEAK T 7 650.0
5946 GIASTSDPPTANIKPTPVVSTPSK T 16 1672.0
6024 RPSTSQTVSTPAPVPVIESTEAIEAK S 9 652.0
6071 LQTTLR T 3 2330.0
10000768 GIASTSDPPTANIKPTPVVSTPSK S 20 1676
10002925 SGMLQAEKK S 1 1318
10003197 TTPASGERGIASTSDPPTANIKPTPVVSTPSK S 28 1676
10004602 FGPPEDMPQTSSSHSDLGQLASQGGLGMYETPLFLAHEEESGGR S 11 2176
10004619 GIASTSDPPTANIKPTPVVSTPSK S 20 1676
10005682 TSDPPTANIKPTPVVSTPSKVTAAAMAGNKS S 1676
10007246 TETMNVVMETNKMLR T 1266
10007247 GIASTSDPPTANIKPTPVVSTPSK S 1676
10010310 EQQPSSASER S 6 2061
10010319 GIASTSDPPTANIK S 6 1662
10010491 VTAAAMAGNKSTPR S 11 1691
10010598 LQTTLR T 4 2331
10010637 GIASTSDPPTANIKPTPVVSTPSK T 21 1677
10010795 GIASTSDPPTANIKPTPVVSTPSK S 20 1676
10011772 GIASTSDPPTANIKPTPVVSTPSK T 16 1672
10012162 GIASTSDPPTANIKPTPVVSTPSK T 10 1666
10015786 GIASTSDPPTANIKPTPVVSTPSK S 20 1676
10016099 TTPASGERGIASTSDPPTANIKPTPVVSTPSK S 28 1676
10016110 TTPASGERGIASTSDPPTANIKPTPVVSTPSK S 28 1676
10016121 TTPASGERGIASTSDPPTANIKPTPVVSTPSK S 28 1676
10016624 GIASTSDPPTANIKPTPVVSTPSK S 20 1676
10018192 NIAIQSQFTRTK S 6 111
10018283 TETMNVVMETNKMLR T 10 1275
10019541 1676
10022194 1676
10024018 1676
10025799 GIASTSDPPTANIKPTPVVSTPSK T 21 1677
10025800 GIASTSDPPTANIKPTPVVSTPSK S 20 1676
10025801 GIASTSDPPTANIKPTPVVSTPSK T 10 1666
10027022 GIASTSDPPTANIKPTPVVSTPSK S 20 1676
10027808 GIASTSDPPTANIKPTPVVSTPSK T 16 1672
10028039 GIASTSDPPTANIKPTPVVSTPSK S 6 1662
10028494 VTAAAMAGNK T 2 1682
10028672 GIASTSDPPTANIKPTPVVSTPSK T 5 1661
10028984 GIASTSDPPTANIKPTPVVSTPSK S 4 1660
10029316 GIASTSDPPTANIKPTPVVSTPSK S 4 1660
10029857 GIASTSDPPTANIKPTPVVSTPSK S 20 1676
10029858 GIASTSDPPTANIKPTPVVSTPSK S 23 1679
10030950 GIASTSDPPTANIKPTPVVSTPSK S 20 1676
10031498 S 1676
10032052 PTPVVSTPSK S 9 1679
10032254 PTPVVSTPSK T 2 1672
10032255 GIASTSDPPTANIKPTPVVSTPSK S 23 1679
10032570 GIASTSDPPTANIKPTPVVSTPSK S 4 1660
10032992 PTPVVSTPSK T 7 1677
10033673 GIASTSDPPTANIKPTPVVSTPSK S 1676
10035597 GIASTSDPPTANIKPTPVVSTPSK S 20 1676

O-GlcNAcylation Information

ID Method Analytical Throughput Ambiguity Species Sample Type Data Source PMID Comments
497 MS HTP None human HeLa cells 21158410 None
498 MS HTP None human HeLa cells 21158410 None
499 MS HTP None human HeLa cells 21158410 None
500 MS HTP None human HeLa cells 21158410 None
2061 MS HTP None human T cells 29351928 None
2062 MS HTP None human T cells 29351928 None
2063 MS HTP None human T cells 29351928 None
2064 MS HTP None human T cells 29351928 None
2065 MS HTP None human T cells 29351928 None
5531 MS HTP None human HeLa cells 31373491 None
5533 MS HTP None human HeLa cells 31373491 None
5564 MS HTP None human HeLa cells 31373491 None
5687 MS HTP None human HeLa cells 31373491 None
5816 MS HTP None human HeLa cells 31373491 None
5946 MS HTP None human HeLa cells 31373491 None
6024 MS HTP None human HeLa cells 31373491 None
6071 MS HTP None human HeLa cells 31373491 None
10000768 MS HTP None human HeLa cells 20068230 None
10002925 MS HTP None human BG02 cells 25367160 None
10003197 MS HTP None human HeLa cells 27114449 None
10004602 MS HTP None human T cells 29351928 None
10004619 MS HTP None human T cells 29351928 None
10005682 MS HTP None human HeLa cells 30059200 None
10007246 MS HTP None human HeLa cells 30379171 None
10007247 MS HTP None human HeLa cells 30379171 None
10010310 MS HTP None human HeLa cells 31373491 None
10010319 MS HTP None human HeLa cells 31373491 None
10010491 MS HTP None human HeLa cells 31373491 None
10010598 MS HTP None human HeLa cells 31373491 None
10010637 MS HTP None human HeLa cells 31373491 None
10010795 MS HTP None human HeLa cells 31492838 None
10011772 MS HTP None human MCF-7 cells 32574038 None
10012162 MS HTP None human MCF-7 cells 32574038 None
10015786 MS HTP None human HeLa cells 20068230 None
10016099 MS HTP None human HeLa cells 27114449 None
10016110 MS HTP None human HeLa cells 27114449 None
10016121 MS HTP None human HeLa cells 27114449 None
10016624 MS HTP None human HeLa cells 30059200 None
10018192 MS HTP None human HeLa cells 33465208 None
10018283 MS HTP None human HeLa cells 33465208 None
10019541 MS HTP None human HeLa cells 34161081 None
10022194 MS HTP None human HeLa cells 34161081 None
10024018 MS HTP None human colorectal cancer (CRC) cell lines 35254053 None
10025799 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10025800 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10025801 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10027022 MS HTP None human HeLa cells 35254053 None
10027808 MS HTP None human HeLa cells 35254053 None
10028039 MS HTP None human HeLa cells 35254053 None
10028494 MS HTP None human HeLa cells 35254053 None
10028672 MS HTP None human HeLa cells 35254053 None
10028984 MS HTP None human HeLa cells 35254053 None
10029316 MS HTP None human SW480 cells 35254053 None
10029857 MS HTP None human SW480 cells 35254053 None
10029858 MS HTP None human SW480 cells 35254053 None
10030950 MS HTP None human SW620 cells 35254053 None
10031498 MS HTP None human SW480 cells, SW620 cells 35254053 None
10032052 MS HTP None human HeLa cell nucleus 35289036 None
10032254 MS HTP None human HeLa cell nucleus 35289036 None
10032255 MS HTP None human HeLa cell nucleus 35289036 None
10032570 MS HTP None human HeLa cell nucleus 35289036 None
10032992 MS HTP None human HeLa cell nucleus 35289036 None
10033673 MS HTP None human MCF-7 cells 35513511 None
10035597 MS HTP None human PANC-1 cells 36240223 None
ID Peptide Seq Site Residue Position in Peptide Position in Protein Method Analytical Throughput Ambiguity Species Sample Type Data Source PMID Comments
497 GIASTSDPPTANIKPTPVVSTPSK T 10 1666.0 MS HTP None human HeLa cells 21158410 None
498 GIASTSDPPTANIKPTPVVSTPSK T 16 1672.0 MS HTP None human HeLa cells 21158410 None
499 GIASTSDPPTANIKPTPVVSTPSK S 20 1676.0 MS HTP None human HeLa cells 21158410 None
500 GIASTSDPPTANIKPTPVVSTPSK T 21 1677.0 MS HTP None human HeLa cells 21158410 None
2061 FGPPEDMPQTSSSHSDLGQLASQGGLGMYETPLFLAHEEESGGR S 22 2187.0 MS HTP None human T cells 29351928 None
2062 GIASTSDPPTANIKPTPVVSTPSK T 16 1672.0 MS HTP None human T cells 29351928 None
2063 GIASTSDPPTANIKPTPVVSTPSK T 21 1677.0 MS HTP None human T cells 29351928 None
2064 GIASTSDPPTANIKPTPVVSTPSK S 23 1679.0 MS HTP None human T cells 29351928 None
2065 SSNIVEVVQSSPVERPSTSTAVF S 11 1804.0 MS HTP None human T cells 29351928 None
5531 EQQPSSASER S 8 2063.0 MS HTP None human HeLa cells 31373491 None
5533 EQQPSSASER S 5 2060.0 MS HTP None human HeLa cells 31373491 None
5564 GIASTSDPPTANIK S 4 1660.0 MS HTP None human HeLa cells 31373491 None
5687 GIASTSDPPTANIKPTPVVSTPSK S 20 1676.0 MS HTP None human HeLa cells 31373491 None
5816 RPSTSQTVSTPAPVPVIESTEAIEAK T 7 650.0 MS HTP None human HeLa cells 31373491 None
5946 GIASTSDPPTANIKPTPVVSTPSK T 16 1672.0 MS HTP None human HeLa cells 31373491 None
6024 RPSTSQTVSTPAPVPVIESTEAIEAK S 9 652.0 MS HTP None human HeLa cells 31373491 None
6071 LQTTLR T 3 2330.0 MS HTP None human HeLa cells 31373491 None
10000768 GIASTSDPPTANIKPTPVVSTPSK S 20 1676 MS HTP None human HeLa cells 20068230 None
10002925 SGMLQAEKK S 1 1318 MS HTP None human BG02 cells 25367160 None
10003197 TTPASGERGIASTSDPPTANIKPTPVVSTPSK S 28 1676 MS HTP None human HeLa cells 27114449 None
10004602 FGPPEDMPQTSSSHSDLGQLASQGGLGMYETPLFLAHEEESGGR S 11 2176 MS HTP None human T cells 29351928 None
10004619 GIASTSDPPTANIKPTPVVSTPSK S 20 1676 MS HTP None human T cells 29351928 None
10005682 TSDPPTANIKPTPVVSTPSKVTAAAMAGNKS S 1676 MS HTP None human HeLa cells 30059200 None
10007246 TETMNVVMETNKMLR T 1266 MS HTP None human HeLa cells 30379171 None
10007247 GIASTSDPPTANIKPTPVVSTPSK S 1676 MS HTP None human HeLa cells 30379171 None
10010310 EQQPSSASER S 6 2061 MS HTP None human HeLa cells 31373491 None
10010319 GIASTSDPPTANIK S 6 1662 MS HTP None human HeLa cells 31373491 None
10010491 VTAAAMAGNKSTPR S 11 1691 MS HTP None human HeLa cells 31373491 None
10010598 LQTTLR T 4 2331 MS HTP None human HeLa cells 31373491 None
10010637 GIASTSDPPTANIKPTPVVSTPSK T 21 1677 MS HTP None human HeLa cells 31373491 None
10010795 GIASTSDPPTANIKPTPVVSTPSK S 20 1676 MS HTP None human HeLa cells 31492838 None
10011772 GIASTSDPPTANIKPTPVVSTPSK T 16 1672 MS HTP None human MCF-7 cells 32574038 None
10012162 GIASTSDPPTANIKPTPVVSTPSK T 10 1666 MS HTP None human MCF-7 cells 32574038 None
10015786 GIASTSDPPTANIKPTPVVSTPSK S 20 1676 MS HTP None human HeLa cells 20068230 None
10016099 TTPASGERGIASTSDPPTANIKPTPVVSTPSK S 28 1676 MS HTP None human HeLa cells 27114449 None
10016110 TTPASGERGIASTSDPPTANIKPTPVVSTPSK S 28 1676 MS HTP None human HeLa cells 27114449 None
10016121 TTPASGERGIASTSDPPTANIKPTPVVSTPSK S 28 1676 MS HTP None human HeLa cells 27114449 None
10016624 GIASTSDPPTANIKPTPVVSTPSK S 20 1676 MS HTP None human HeLa cells 30059200 None
10018192 NIAIQSQFTRTK S 6 111 MS HTP None human HeLa cells 33465208 None
10018283 TETMNVVMETNKMLR T 10 1275 MS HTP None human HeLa cells 33465208 None
10019541 1676 MS HTP None human HeLa cells 34161081 None
10022194 1676 MS HTP None human HeLa cells 34161081 None
10024018 1676 MS HTP None human colorectal cancer (CRC) cell lines 35254053 None
10025799 GIASTSDPPTANIKPTPVVSTPSK T 21 1677 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10025800 GIASTSDPPTANIKPTPVVSTPSK S 20 1676 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10025801 GIASTSDPPTANIKPTPVVSTPSK T 10 1666 MS HTP None human Jurkat cells, MCF-7 cells, K562 cells 35132862 None
10027022 GIASTSDPPTANIKPTPVVSTPSK S 20 1676 MS HTP None human HeLa cells 35254053 None
10027808 GIASTSDPPTANIKPTPVVSTPSK T 16 1672 MS HTP None human HeLa cells 35254053 None
10028039 GIASTSDPPTANIKPTPVVSTPSK S 6 1662 MS HTP None human HeLa cells 35254053 None
10028494 VTAAAMAGNK T 2 1682 MS HTP None human HeLa cells 35254053 None
10028672 GIASTSDPPTANIKPTPVVSTPSK T 5 1661 MS HTP None human HeLa cells 35254053 None
10028984 GIASTSDPPTANIKPTPVVSTPSK S 4 1660 MS HTP None human HeLa cells 35254053 None
10029316 GIASTSDPPTANIKPTPVVSTPSK S 4 1660 MS HTP None human SW480 cells 35254053 None
10029857 GIASTSDPPTANIKPTPVVSTPSK S 20 1676 MS HTP None human SW480 cells 35254053 None
10029858 GIASTSDPPTANIKPTPVVSTPSK S 23 1679 MS HTP None human SW480 cells 35254053 None
10030950 GIASTSDPPTANIKPTPVVSTPSK S 20 1676 MS HTP None human SW620 cells 35254053 None
10031498 S 1676 MS HTP None human SW480 cells, SW620 cells 35254053 None
10032052 PTPVVSTPSK S 9 1679 MS HTP None human HeLa cell nucleus 35289036 None
10032254 PTPVVSTPSK T 2 1672 MS HTP None human HeLa cell nucleus 35289036 None
10032255 GIASTSDPPTANIKPTPVVSTPSK S 23 1679 MS HTP None human HeLa cell nucleus 35289036 None
10032570 GIASTSDPPTANIKPTPVVSTPSK S 4 1660 MS HTP None human HeLa cell nucleus 35289036 None
10032992 PTPVVSTPSK T 7 1677 MS HTP None human HeLa cell nucleus 35289036 None
10033673 GIASTSDPPTANIKPTPVVSTPSK S 1676 MS HTP None human MCF-7 cells 35513511 None
10035597 GIASTSDPPTANIKPTPVVSTPSK S 20 1676 MS HTP None human PANC-1 cells 36240223 None