Details for Accession #: P11388

Protein Sequence

>sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3
MEVSPLQPVNENMQVNKIKKNEDAKKRLSVERIYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWMDNMGRAGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKLDETGNSLKVIHEQVNHRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQPKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQ
VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD
RKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDVREIVNNIRRLMDGEEPLPMLPSYKNFKGTIE
ELAPNQYVISGEVAILNSTTIEISELPVRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDNEKETEKSDSVTDSGPTFNYLLDMPLWYLTKEK
KDELCRLRNEKEQELDTLKRKSPSDLWKEDLATFIEELEAVEAKEKQDEQVGLPGKGGKA
KGKKTQMAEVLPSPRGQRVIPRITIEMKAEAEKKNKKKIKNENTEGSPQEDGVELEGLKQ
RLEKKQKREPGTKTKKQTTLAFKPIKKGKKRNPWSDSESDRSSDESNFDVPPRETEPRRA
ATKTKFTMDLDSDEDFSDFDEKTDDEDFVPSDASPPKTKTSPKLSNKELKPQKSVVSDLE
ADDVKGSVPLSSSPPATHFPDETEITNPVPKKNVTVKKTAAKSQSSTSTTGAKKRAAPKG
TKRDPALNSGVSQKPDPAKTKNRRKRKPSTSDDSDSNFEKIVSKAVTSKKSKGESDDFHM
DFDSAVAPRAKSVRAKKPIKYLEESDEDDLF

Peptide Information

ID Peptide Seq Site Residue Position in Peptide Position in Protein
11463 ENMTLQPKSFGSTCQLSEK S 9 387.0
11464 ENMTLQPKSFGSTCQLSEK S 12 390.0
11468 SQSSTSTTGAKKR S 3 1425.0
11469 SQSSTSTTGAKKR S 4 1426.0
11470 SQSSTSTTGAKKR T 5 1427.0
11471 SQSSTSTTGAKKR S 6 1428.0
11548 PSTSDDSDSNFEKIVSK S 2 1469.0
11549 PSTSDDSDSNFEKIVSK T 3 1470.0
10007233 IVSKAVTSK S 1488
10007234 IVSKAVTSK T 1487
10007235 SVVSDLEADDVK S 1374
10018148 YSGPEDDAAISLAFSK S 2 641
10018149 YSGPEDDAAISLAFSK S 15 654
10018323 ENMTLQPKSFGSTCQLSEK S 17 395
10018335 SQSSTSTTGAKKR S 1 1423
10018509 PSTSDDSDSNFEKIVSK S 4 1471

O-GlcNAcylation Information

ID Method Analytical Throughput Ambiguity Species Sample Type Data Source PMID Comments
11463 MS HTP None human HeLa cells 33465208 None
11464 MS HTP None human HeLa cells 33465208 None
11468 MS HTP None human HeLa cells 33465208 None
11469 MS HTP None human HeLa cells 33465208 None
11470 MS HTP None human HeLa cells 33465208 None
11471 MS HTP None human HeLa cells 33465208 None
11548 MS HTP None human HeLa cells 33465208 None
11549 MS HTP None human HeLa cells 33465208 None
10007233 MS HTP None human HeLa cells 30379171 None
10007234 MS HTP None human HeLa cells 30379171 None
10007235 MS HTP None human HeLa cells 30379171 None
10018148 MS HTP None human HeLa cells 33465208 None
10018149 MS HTP None human HeLa cells 33465208 None
10018323 MS HTP None human HeLa cells 33465208 None
10018335 MS HTP None human HeLa cells 33465208 None
10018509 MS HTP None human HeLa cells 33465208 None
ID Peptide Seq Site Residue Position in Peptide Position in Protein Method Analytical Throughput Ambiguity Species Sample Type Data Source PMID Comments
11463 ENMTLQPKSFGSTCQLSEK S 9 387.0 MS HTP None human HeLa cells 33465208 None
11464 ENMTLQPKSFGSTCQLSEK S 12 390.0 MS HTP None human HeLa cells 33465208 None
11468 SQSSTSTTGAKKR S 3 1425.0 MS HTP None human HeLa cells 33465208 None
11469 SQSSTSTTGAKKR S 4 1426.0 MS HTP None human HeLa cells 33465208 None
11470 SQSSTSTTGAKKR T 5 1427.0 MS HTP None human HeLa cells 33465208 None
11471 SQSSTSTTGAKKR S 6 1428.0 MS HTP None human HeLa cells 33465208 None
11548 PSTSDDSDSNFEKIVSK S 2 1469.0 MS HTP None human HeLa cells 33465208 None
11549 PSTSDDSDSNFEKIVSK T 3 1470.0 MS HTP None human HeLa cells 33465208 None
10007233 IVSKAVTSK S 1488 MS HTP None human HeLa cells 30379171 None
10007234 IVSKAVTSK T 1487 MS HTP None human HeLa cells 30379171 None
10007235 SVVSDLEADDVK S 1374 MS HTP None human HeLa cells 30379171 None
10018148 YSGPEDDAAISLAFSK S 2 641 MS HTP None human HeLa cells 33465208 None
10018149 YSGPEDDAAISLAFSK S 15 654 MS HTP None human HeLa cells 33465208 None
10018323 ENMTLQPKSFGSTCQLSEK S 17 395 MS HTP None human HeLa cells 33465208 None
10018335 SQSSTSTTGAKKR S 1 1423 MS HTP None human HeLa cells 33465208 None
10018509 PSTSDDSDSNFEKIVSK S 4 1471 MS HTP None human HeLa cells 33465208 None